Byzantine–Ottoman wars: The Empire of Trebizond, the longest-surviving Byzantine successor state, was conquered by Ottoman forces following a month-long siege.

The Byzantine–Ottoman wars were a series of decisive conflicts between the Byzantine Greeks and Ottoman Turks and their allies that led to the final destruction of the Byzantine Empire and the rise of the Ottoman Empire. The Byzantines, already having been in a weak state even before the dismemberment of their Empire following the Fourth Crusade, failed to recover fully under the rule of the Palaiologos dynasty. Thus, the Byzantines faced increasingly disastrous defeats at the hands of the Ottomans. Ultimately, they lost Constantinople in 1453, formally ending the conflicts.