Harriet Beecher Stowe's anti-slavery serial, Uncle Tom's Cabin, or Life Among the Lowly, starts a ten-month run in the National Era abolitionist newspaper.

Harriet Elisabeth Beecher Stowe was an American author and abolitionist. She came from the religious Beecher family and wrote a popular novel called Uncle Tom's Cabin (1852), which depicts the harsh conditions experienced by enslaved African Americans. The book reached an audience of millions as a novel and play and was influential in the United States and in Great Britain, energizing anti-slavery forces in the American North, while provoking widespread anger in the South. Stowe wrote 30 books, including novels, three travel memoirs, and collections of articles and letters. She was influential both for her writings and for her public stances and debates on social issues of the day.